Sustained reduction in coagulation activity during long-term dalteparin treatment in unstable coronary artery disease

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Coagulation activity and clinical outcome in unstable coronary artery disease.

In the current study, we investigated molecular markers of coagulation activity, ie, prothrombin fragment 1+2 (F1+2), thrombin-antithrombin (TAT) complex, soluble fibrin (SF), and D-dimer, and their relation to death, myocardial infarction, and refractory angina during and after anticoagulant treatment in unstable coronary artery disease. Patients with unstable coronary artery disease (N=320) w...

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Benefits of extended treatment with dalteparin in patients with unstable coronary artery disease eligible for revascularization.

AIMS The FRISC II trial demonstrated that, for patients with unstable coronary artery disease, an early invasive strategy following acute treatment with dalteparin and aspirin, was superior to a more conservative approach. We evaluated whether it is beneficial to extend treatment with dalteparin to patients eligible for revascularization but for whom these procedures are performed after the ini...

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Patients with unstable coronary artery disease (CAD), i.e., unstable angina or non-ST-elevation myocardial infarction, vary widely in clinical presentation, prognosis and response to treatment. To select appropriate therapy, early risk stratification has become increasingly important. This review focuses on the emerging role of natriuretic peptides in the early assessment of patients with unsta...

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Risk Stratification in Unstable Coronary Artery Disease

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2002

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(02)81502-9